Massimo Mazzotti's research interests lie at the intersection of the history of science and science studies. He is especially interested in the historicity and situatedness of mathematics, logic, and deductive reasoning, and in the social processes that can make them universally valid. He is also interested in using technological systems and artifacts as ways of entry for the explorations of specific forms of social organization and power distribution. His past and present research projects have focused primarily on the early modern and Enlightenment period, with significant incursions into the nineteenth and twentieth century.